This track shows DNase hypersensitive areas assayed in a 95 cell types by the John Stamatoyannapoulos lab at the University of Washington as part ENCODE project during the first production and analysis phase of the project (Sept. 2007 - Jan 2011). Regulatory regions in general, and promoters in particular, tend to be DNase-sensitive.
Additional views of this data and additional documentation on the methods used to identify hypersensitive sites are available from the UW DNaseI HS track. The peaks in that track are the basis for the clusters shown here, which combine data from the peaks of the different cell lines.A gray box indicates the extent of the hypersensitive region. The darkness is proportional to the maximum signal strength observed in any cell line. The number to the left of the box shows how many cell lines are hypersensitive in the region. The track can be configured to restrict the display to elements above a specified score in the range 1-1000 (where score is based on signal strength).
Peaks of DNaseI hypersensitivity from the ENCODE DNase Analysis Pipeline at UCSC were assigned normalized scores (by UCSC regClusterMakeTableOfTables) in the range 0-1000 based on the narrowPeak signalValue and then clustered on score (by UCSC regCluster) to generate singly-linked clusters.
This track is based on sequence data from the University of Washington ENCODE group, with subsequent processing by UCSC. For additional credits and references, see the UW DNaseI HS track.