Description

This track shows Evolutionary Conserved Regions computed by the Exofish (Roest et al., 2000) program at Genoscope. Each singleton block corresponds to an "ecore"; two blocks connected by a thin line correspond to an "ecotig", a set of colinear ecores in a syntenic region.

Methods

Genome-wide sequence comparisons were done at the protein-coding level between the genome sequences of the fruitfly, Drosophila melanogaster and the mosquito, Anopheles gambiae to detect evolutionarily conserved regions (ECORES). See Jaillon et al., 2003. The sequence versions used in the comparison were Ensembl Drosophila v.16.3a.1 (Jan. 2003, the same as BDGP Release 3.1 used by the UCSC Genome Browser) and Ensembl Anopheles v.16.2.1 .

Credits

Thanks to Olivier Jaillon at Genoscope for contributing the data.

References

Jaillon O, Dossat C, Eckenberg R, Eiglmeier K, Segurens B, Aury JM, Roth CW, Scarpelli C, Brey PT, Weissenbach J et al. Assessing the Drosophila melanogaster and Anopheles gambiae genome annotations using genome-wide sequence comparisons. Genome Res. 2003 Jul;13(7):1595-9. PMID: 12840038; PMC: PMC403732

Roest Crollius H, Jaillon O, Bernot A, Dasilva C, Bouneau L, Fischer C, Fizames C, Wincker P, Brottier P, Quétier F et al. Estimate of human gene number provided by genome-wide analysis using Tetraodon nigroviridis DNA sequence. Nat Genet. 2000 Jun;25(2):235-8. PMID: 10835645