This directory contains alignments of the following assemblies:

  - target/reference: Dog
    (canFam3, Sep. 2011 (Broad CanFam3.1/canFam3),
    Broad CanFam3.1 (GCA_000002285.2))

  - query: Rat
    (rn6, Jul. 2014 (RGSC 6.0/rn6),
    RGSC Rnor_6.0)

Files included in this directory:

  - md5sum.txt: md5sum checksums for the files in this directory

  - canFam3.rn6.all.chain.gz: chained lastz alignments. The chain format is
    described in .

  - "net" file that describes rearrangements between
    the species and the best Rat match to any part of the
    Dog genome.  The net format is described in .

  - chained and netted alignments,
    i.e. the best chains in the Dog genome, with gaps in the best
    chains filled in by next-best chains where possible.  The axt format is
    described in .

  - canFam3.rn6.synNet.maf.gz - filtered net file for syntenic alignments
               only, in MAF format, see also, description of MAF format:

  - - filtered net file for syntenic alignments only

  - reciprocalBest/ directory, contains reciprocal-best netted chains
    for canFam3-rn6

The chainSwap program was used to translate rn6-referenced chained lastz
alignments to canFam3 into canFam3-referenced chains aligned to rn6.  See
the download directory goldenPath/rn6/vsCanFam3/README.txt for more
information about the rn6-referenced lastz and chaining process.

Chained alignments were processed into nets by the chainNet, netSyntenic,
and netClass programs.
Best-chain alignments in axt format were extracted by the netToAxt program.
All programs run after lastz were written by Jim Kent at UCSC.

If you plan to download a large file or multiple files from this directory,
we recommend you use ftp rather than downloading the files via our website.
To do so, ftp to, then go to the directory
goldenPath/canFam3/vsRn6/. To download multiple files, use the "mget"

    mget <filename1> <filename2> ...
    - or -
    mget -a (to download all files in the current directory)

All files in this directory are freely available for public use.


Chiaromonte F, Yap VB, Miller W. Scoring pairwise genomic sequence
alignments. Pac Symp Biocomput.  2002:115-26.

Kent WJ, Baertsch R, Hinrichs A, Miller W, Haussler D.
Evolution's cauldron: Duplication, deletion, and rearrangement in the
mouse and human genomes. Proc Natl Acad Sci U S A. 2003 Sep

Schwartz S, Kent WJ, Smit A, Zhang Z, Baertsch R, Hardison RC,
Haussler D, Miller W. Human-Mouse Alignments with BLASTZ. Genome
Res. 2003 Jan;13(1):103-7.

      Name                      Last modified      Size  Description
Parent Directory - canFam3.rn6.all.chain.gz 14-Jan-2017 18:08 183M 14-Jan-2017 18:25 549M 14-Jan-2017 18:44 145M 19-Jan-2017 10:36 138M canFam3.rn6.synNet.maf.gz 19-Jan-2017 10:47 525M md5sum.txt 19-Jan-2017 10:47 286 reciprocalBest/ 15-Jan-2017 03:34 -