The miRNA track shows microRNAs from miRBase.
The precursor forms of microRNAs (mirs) are represented by thin blocks. miRNAs in the sense orientation are shown in black; those in the reverse orientation are colored grey.
To display only those items that exceed a specific unnormalized score, enter a minimum score between 0 and 1000 in the text box at the top of the track description page.
Precursor miRNAs from miRBase were aligned against the genome using blat. The extents of the precursor sequences were not generally known, and were predicted based on base-paired hairpin structure. miRBase is described in Griffiths-Jones, S. et al. (2006). The miRNA Registry is described in Griffiths-Jones, S. (2004) and Weber, M.J. (2005) in the References section below.
This track was created by Michel Weber of Laboratoire de Biologie Moléculaire Eucaryote, CNRS Université Paul Sabatier (Toulouse, France), Yves Quentin of Laboratoire de Microbiologie et Génétique Moléculaires (Toulouse, France) and Sam Griffiths-Jones of The Wellcome Trust Sanger Institute (Cambridge, UK).
When making use of these data, please cite:
Griffiths-Jones S. The microRNA Registry. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D109-11. PMID: 14681370; PMC: PMC308757
Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A, Enright AJ. miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4. PMID: 16381832; PMC: PMC1347474
Weber MJ. New human and mouse microRNA genes found by homology search. FEBS J. 2005 Jan;272(1):59-73. PMID: 15634332
The following publication provides guidelines on miRNA annotation:
Ambros V, Bartel B, Bartel DP, Burge CB, Carrington JC, Chen X, Dreyfuss G, Eddy SR, Griffiths-Jones
S, Marshall M et al.
A uniform system for microRNA annotation.
RNA. 2003 Mar;9(3):277-9.
PMID: 12592000; PMC: PMC1370393
For more information on blat, see
Kent WJ.
BLAT--the BLAST-like alignment tool.
Genome Res. 2002 Apr;12(4):656-64.
PMID: 11932250; PMC: PMC187518