This directory contains GERP (Genomic Evolutionary Rate Profiling)
scores for the multiple sequence alignments in the Sep-2005 ENCODE
MSA sequence freeze.

GERP was developed primarily by Greg Cooper in the lab of Arend Sidow at Stanford University (Depts of Pathology and Genetics), in close collaboration with Eric Stone (Biostatistics, NC State), and George Asimenos and Eugene Davydov in the lab of Serafim Batzoglou (Dept. of Computer Science, Stanford).

For more information, see the GERP section of the
track description for the ENCODE TBA Conservation
track in the Human May 2004 (hg17) genome browser,
and the GERP web page at the Sidow lab:
    http://mendel.stanford.edu/sidowlab/downloads/ABC_GERP/abcgerp.html
and the publication:

Cooper, et. al.
"Distribution and intensity of constraint in mammalian genomic sequence"
Genome Research, July 2005
http://www.genome.org/cgi/content/abstract/15/7/901

      Name                                                      Last modified      Size  Description
      Parent Directory                                                               -   
      md5sum.txt                                                2007-04-16 13:39  176   
      GERP_TBA.scores.wig.gz                                    2007-04-16 11:39   29M  
      GERP_MLAGAN.scores.wig.gz                                 2007-04-16 11:39   35M  
      GERP_MAVID.scores.wig.gz                                  2007-04-16 11:39   24M