Comparison of the Human Genome Working Draft with Other Maps
Here we show the positions of STS markers on the assembly of the working draft human genome sequence versus their positions in various maps.

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These plots are described more fully in Initial sequencing and analysis of the human genome by the International Human Genome Sequencing Consortium, Nature,409: 860-921, 2001. Included are the Genethon genetic map, the Marshfield genetic map, the deCODE genetic map, the GeneMap99 radiation hybrid map, the G3 and TNG radiation hybrid maps, the Whitehead YAC and RH maps, and the resource of FISH-mapped BAC clones ( NCBI Clone Registry). We thank the researchers who built these maps for making their data available.

The TNG map data is discussed in Olivier et al., "A high resolution radiation hybrid map of the human genome draft sequence," Science 291(5507):1298-1303, 2001, and the cytogenetic data in "Integration of cytogenetic landmarks into the draft sequence of the human genome," by the BAC Resource Consortium, Nature, Vol. 409:953-958, 2001.

Data for sex-averaged Genethon, sex-averaged Marshfield, GeneMap99 RH, G3 RH and Whitehead YAC maps was first collected into a unified database by Greg Schuler at NCBI. Prior to the December freeze, we also used his e-pcr program (very slightly modified) to place the markers on the draft sequence, with the exception of the FISH-mapped clones, which were placed by Wonhee Jang and Greg Schuler at NCBI, with assistance from Arek Kasprzyk and Ewan Birney at EBI. Starting with the December freeze, we began placing all markers and FISH-mapped clones ourselves by matching the full STS sequence to the golden path whenever possible, not just the primers. BAC ends and accession information were also used to help place the FISH-mapped clones.