MethBase is a central reference methylome database created from public BS-seq datasets. The Smith Lab at USC maintained MethBase between 2012 and 2023. MethBase is now frozen and no new data will be added. MethBase includes 605 DNA methylation profiles reprocessed from sequencing data in NCBI SRA. The methods used to process data for MethBase can be found here. Additional information can be found in the description pages for individual tracks at the UCSC Genome Browser.
We continue to add methylomes to MethBase2, and MethBase2 has a track hub listed among the public hubs at the UCSC Genome Browser.
Song Q, Decato B, Hong EE, Zhou M, Fang F, Qu J, Garvin T, Kessler M, Zhou J, Smith AD. A reference methylome database and analysis pipeline to facilitate integrative and comparative epigenomics. PLoS One. 2013;8(12):e81148. PMID: 24324667; PMC: PMC3855694